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PROSS: the Protein Repair One-Stop Shop



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Pross Terms
Upload PDB?
Files
Structure info
AlphaFold2 confidence
Constraints
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MSA file
MSA
Energy function

PROSS is a protein stability-design method, and its academic use is free. If academic use of the results leads to applications with commercial potential, please obtain a license to the results from the Weizmann Institute’s technology transfer office Yeda. Commercial users or academic users conducting commercially sponsored research should refer to Scala Biodesign which holds an exclusive license for such uses.

Must be a named account belonging to a valid academic domain
Full name of the head of research lab
Write "Yes" or "No". Commercial users, please contact Scala Biodesign
Write "Yes" or "No". For sponsored research, please contact Scala Biodesign
Write "Yes" or "No"

NEW! a Hands-on tutorial for using the Fleishman lab
protein-optimisation workflows

Selected PROSS, FuncLib & CUMAb citations and patents

Questions and support
Overview & questions: contact us
See also our About PROSS page

Commercial users
Please contact Scala Biodesign


Citation
Please cite Goldenzweig et al. Mol Cell 2016
PMID: 27425410 PDF HTML

Algorithm development
Adi Goldenzweig & Sarel Fleishman
Additional contributions: Jonathan Weinstein
Web interface: Jaime Prilusky and Shi Hoch

Terms and conditions
Use of the output, the variants and their derivatives is subject to the terms and conditions and may be used for academic research only, excluding commercially sponsored research. Accordingly, commercial use of the attached variants or their derivatives is unauthorized without prior written approval by Yeda.